Item Type | Name |
Concept
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Vascular Endothelial Growth Factor A
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Concept
|
Granulocyte Colony-Stimulating Factor
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Concept
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Transforming Growth Factor beta
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Concept
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E2F7 Transcription Factor
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Concept
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E2F6 Transcription Factor
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Concept
|
Receptor, Platelet-Derived Growth Factor alpha
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Concept
|
E2F4 Transcription Factor
|
Concept
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Transcription Factor DP1
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Concept
|
Receptor, Platelet-Derived Growth Factor beta
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Concept
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Platelet-Derived Growth Factor
|
Concept
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STAT5 Transcription Factor
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Concept
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Peptide Elongation Factor 2
|
Concept
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STAT3 Transcription Factor
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Concept
|
Receptor, Fibroblast Growth Factor, Type 2
|
Concept
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E2F3 Transcription Factor
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Concept
|
Hypoxia-Inducible Factor 1
|
Concept
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E2F1 Transcription Factor
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Concept
|
Tumor Necrosis Factor-alpha
|
Concept
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Growth Differentiation Factor 15
|
Concept
|
E2F5 Transcription Factor
|
Concept
|
Hepatocyte Growth Factor
|
Concept
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E2F2 Transcription Factor
|
Concept
|
Transforming Growth Factor alpha
|
Concept
|
Eukaryotic Initiation Factor-4F
|
Concept
|
Epidermal Growth Factor
|
Concept
|
Macrophage Colony-Stimulating Factor
|
Concept
|
Growth Differentiation Factor 10
|
Concept
|
Transcription Factor RelA
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
Academic Article
|
Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis.
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Academic Article
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Inactivation of E2F3 results in centrosome amplification.
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Academic Article
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Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation.
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Academic Article
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Bone morphogenetic protein 3B silencing in non-small-cell lung cancer.
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Academic Article
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Aberrant regulation of survivin by the RB/E2F family of proteins.
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Academic Article
|
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.
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Academic Article
|
Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice.
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Academic Article
|
E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7.
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Academic Article
|
Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.
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Academic Article
|
E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.
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Academic Article
|
Rb is critical in a mammalian tissue stem cell population.
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Academic Article
|
Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions.
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Academic Article
|
Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.
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Academic Article
|
Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis.
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Academic Article
|
Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.
|
Academic Article
|
Mouse development with a single E2F activator.
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Academic Article
|
E2f3a and E2f3b contribute to the control of cell proliferation and mouse development.
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Academic Article
|
E2F3 is a mediator of DNA damage-induced apoptosis.
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Academic Article
|
Division and apoptosis of E2f-deficient retinal progenitors.
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Academic Article
|
E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
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Academic Article
|
E2f1-3 are critical for myeloid development.
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Academic Article
|
Cell proliferation in the absence of E2F1-3.
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Academic Article
|
S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.
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Academic Article
|
Atypical E2F repressors and activators coordinate placental development.
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Academic Article
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E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1.
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Academic Article
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Canonical and atypical E2Fs regulate the mammalian endocycle.
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Academic Article
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Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells.
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Academic Article
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HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer.
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Academic Article
|
Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
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Academic Article
|
FGFR and PTEN signaling interact during lens development to regulate cell survival.
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Academic Article
|
Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice.
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Academic Article
|
E2f8 mediates tumor suppression in postnatal liver development.
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Academic Article
|
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
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Academic Article
|
Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
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Academic Article
|
Loss of fibroblast HIF-1a accelerates tumorigenesis.
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Academic Article
|
Stromal PDGFR-a Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.
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Academic Article
|
IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-?B.
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Academic Article
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E2f3 in tumor macrophages promotes lung metastasis.
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Academic Article
|
CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
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Academic Article
|
NF-?B regulates GDF-15 to suppress macrophage surveillance during early tumor development.
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Academic Article
|
hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.
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Academic Article
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Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.
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Academic Article
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Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis.
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Academic Article
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The E2F1-3 transcription factors are essential for cellular proliferation.
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Academic Article
|
Myc requires distinct E2F activities to induce S phase and apoptosis.
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Academic Article
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E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
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Academic Article
|
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
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Academic Article
|
Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.
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Academic Article
|
Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2.
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Academic Article
|
Atypical E2Fs: new players in the E2F transcription factor family.
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Academic Article
|
QChIPat: a quantitative method to identify distinct binding patterns for two biological ChIP-seq samples in different experimental conditions.
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Academic Article
|
Cited2 is required in trophoblasts for correct placental capillary patterning.
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Academic Article
|
Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs.
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Academic Article
|
Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.
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Academic Article
|
E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.
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Academic Article
|
The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.
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Academic Article
|
Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor.
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Academic Article
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Distinct roles for E2F proteins in cell growth control and apoptosis.
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Academic Article
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Functional analysis of E2F transcription factor.
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Academic Article
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Role of the Rb/E2F pathway in cell growth control.
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Academic Article
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E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2.
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Academic Article
|
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells.
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Academic Article
|
Distinct mechanisms control the accumulation of the Rb-related p107 and p130 proteins during cell growth.
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Academic Article
|
Ras enhances Myc protein stability.
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Academic Article
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Tissue-specific targeting of cell fate regulatory genes by E2f factors.
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Academic Article
|
Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer.
|
Academic Article
|
Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase.
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Academic Article
|
Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins.
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Academic Article
|
Complex transcriptional regulatory mechanisms control expression of the E2F3 locus.
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Academic Article
|
Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-beta1 is a cell cycle-independent effect and influences their hematopoietic potential.
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Academic Article
|
Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway.
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Academic Article
|
Expression of the c-met proto-oncogene and its ligand, hepatocyte growth factor, in Hodgkin disease.
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Academic Article
|
T-cell apoptosis induced by granulocyte colony-stimulating factor is associated with retinoblastoma protein phosphorylation and reduced expression of cyclin-dependent kinase inhibitors.
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Academic Article
|
Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors.
|
Academic Article
|
Stromal Platelet-Derived Growth Factor Receptor-? Signaling Promotes Breast Cancer Metastasis in the Brain.
|
Concept
|
CCCTC-Binding Factor
|
Concept
|
Transcription Factor 7-Like 2 Protein
|
Academic Article
|
Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome.
|
Academic Article
|
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
|
Academic Article
|
Discovery of nonautonomous modulators of activated Ras.
|